The Sequoia has standard Active Headrests, which use a specially designed headrest to protect the driver and front passenger from whiplash. During a rear-end collision, the Active Headrests system moves the headrests forward to prevent neck and spine injuries. The Pilot doesn’t offer a whiplash protection system.
Both the Sequoia and the Pilot have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning and available four-wheel drive.
The Toyota Sequoia weighs 935 to 1879 pounds more than the Honda Pilot. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

